needtoknow
Registered: 04/11/10
Posts: 1
|
| | 04/11/10 at 07:07 PM | Reply with quote | #1 |
|
Ok,
My husbannd has just recently been diagnosed with a rare cancer and we have now been informed that he will be sterile by the time he is done with chemotherapy. I literally have two weeks to figure out my family planning. We are 32 and 33 years old and have wanted to have children in the future but now the doctors are making us figure it out now.
Here's the delema: MD runs in my family on my fathers side. I have been trying to find any information on what the likelyhood of my passing it on would be. Here is who has had it in my family that I know of:
My Grandmother (Fathers Mother) had mild MD only showed with her "grip test" and eventual resperatory issues, My Father does not have it, His sister was clear but his brother had a very severe case and it showed in him at a very young age. Back in the 70's when I was born my parents were told that I could have a 50/50 chance of having but I have shown no signs of it and when I do the "grip test" my reactions are very quick and not delayed.
I cannot find any statistics that match my family history and I do not have time to wait for a gene test to make my decision on having a kid. I also cannot afford to bank sperm for future use, so, it's either now or never.
So, I guess my question is "Is it likely that I'm a carrier and if so, what percentage rate's would my children be affected?
If anyone has any advise, I sure could use it right now.
|
| Loading... | |
pookie
Senior Member
Registered: 03/10/09
Posts: 16
|
| | 04/12/10 at 04:07 AM | Reply with quote | #2 |
|
Hi,
Firstly,really sorry to hear of the situation you and your family have been put in.Unfair doesnt even begin to cover it.
Secondly,i speak with no medical authority and can only comment on what i have learnt from books and dealings with others.
However...if your dad definitely didnt have it and you dont have any symptoms at the age of 32/33 then the chances of you having it would be pretty much zero.I cant find reference to any occurences when myotonic dystrophy has skipped a generation so if your dad didnt have it then I cant see that you can,unless by complete fluke.
I do find it really odd that they told your parents that you would have a 50/50 chance of getting it as this is the rate told to prospective parents like me and my wife who are going for ivf,where one parent definitely has myotonic dystrophy.If your father doesnt have it then the moytonic dystrophy line stops with your dad.end of story.
Obviously you will need to double check what i am saying with someone with the medical qualifications to say for sure,but i can only think in the seventies they didnt know as much about it as they do now,or maybe your father wasnt sure if he had it or not at the time.
Just to clarify my story,my wife has DM without a doubt.we have been told it is 50/50 for any of our children.My wifes sister definitely does not and has been told there is absolutely no chance of her children being at risk of getting it.
I hope i am right and i hope everything works out for you and your family.
very best wishes.
pookie
|
| Loading... | |
pookie
Senior Member
Registered: 03/10/09
Posts: 16
|
| | 04/12/10 at 04:11 AM | Reply with quote | #3 |
|
Just reread your post and need to clarify that my comments relate to myotonic dystrohy only (known as DM in the uk,not sure if its same in u.s.),but you refer to MD so do you mean myotonic dystrophy or to some other possible form of muscular dystrophy? regards
pookie
|
| Loading... | |
debs
Junior Member
Registered: 07/24/08
Posts: 3
|
| | 05/03/10 at 08:53 AM | Reply with quote | #4 |
|
Hi sorry for your bad news. My husband was diagnosed in 2001, some of his siblings have been tested since then, they all came back negative and were told that their children wouldn't be affected as they are clear. We were told that any children we had would have a 50/50 chance of being affected, however my husband is infertile, diagnosed before the MD so we have had four wonderfull children by artificial insemination, so you should be OK. Good luck with the children and your partners fight against C |
| Loading... | |
